Volume 2, Issue 1 (January 2023)                   Health Science Monitor 2023, 2(1): 39-49 | Back to browse issues page

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Hallaj T, Amjadi M, L. Manzoori J. A Sensitive Chemiluminescence Probe Based on Cerium (IV)-Sulfite Reaction for the Determination of Methamphetamine in Biological Samples and Street Drugs. Health Science Monitor 2023; 2 (1) :39-49
URL: http://hsm.umsu.ac.ir/article-1-54-en.html
Cellular and Molecular Research Center, Cellular and Molecular Medicine Institute, Urmia University of Medical Sciences, Urmia, Iran
Abstract:   (525 Views)
Background & Aims: Methamphetamine is one of the most widely abused drugs worldwide. Its rapid and simple detection and determination in street drugs and biological samples are of great importance for forensic science applications.
Materials & Methods: In this work, a simple and sensitive chemiluminescence-based method was established for methamphetamine analysis. It is based on the enhancing effect of methamphetamine on Ce(IV)-Na2SO3 chemiluminescence (CL) reaction. A possible mechanism was discussed for the CL system. Optimization of chemical variables affecting the CL response of the system was performed by an experimental design approach using the central composite design.
Results: Under the optimum conditions, the enhanced CL intensity was proportional to the concentration of methamphetamine in the range of 0.005-5.0 µg/mL, with a detection limit of 1.2 ng/mL.
Conclusion: The developed method applied to determine methamphetamine in street drugs and human plasma samples showed satisfactory results.
Full-Text [PDF 744 kb]   (333 Downloads)    
Type of Study: Research | Subject: General
Received: 2022/08/2 | Accepted: 2023/02/1 | Published: 2023/01/20

1. Katzung BG, Masters SB, Trevor AJ. Basic and Clinical Pharmacology 12/E Inkling (ENHANCED EBOOK). McGraw Hill Professional; 2012. 1245 p. [URL]
2. Fedotov Y. World drug report 2012. New York, NY: United Nations Office on Drugs and Crime (UNODC). 2014:51-3. [URL]
3. Kraemer T, Maurer HH. Determination of amphetamine, methamphetamine and amphetamine-derived designer drugs or medicaments in blood and urine. Journal of Chromatography B: Biomedical Sciences and Applications. 1998 Aug 21;713(1):163-87. [DOI] [PMID]
4. Cerdán-Vidal A, Maurı́-Aucejo AR, Pascual-Martı́ MC, Llobat-Estellés M. Identification and determination of amphetamine and methamphetamine in street drugs. Microchemical Journal. 2000 Apr 30;64(2):201-5. [DOI]
5. Cai Z min, Wu Y fang, Huang Y he, Li Q ping, Chen X mei, Chen X. An electrochemiluminescence sensor based on a Ru(bpy)32+-silica-chitosan/nanogold composite film. Talanta. 2012 May 30;94:356-60. [DOI] [PMID]
6. Shahdousti P, Aghamohammadi M, Alizadeh N. Spectrophotometric study of the charge-transfer and ion-pair complexation of methamphetamine with some acceptors. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 2008 Apr;69(4):1195-200. [DOI] [PMID]
7. Yi C, Tao Y, Wang B, Chen X. Electrochemiluminescent determination of methamphetamine based on tris(2,2′-bipyridine)ruthenium(II) ion-association in organically modified silicate films. Analytica Chimica Acta. 2005 Jun;541(1-2):73-81. [DOI]
8. Teshima N, Fukui N, Sakai T. Reagents regeneration flow injection analysis (RRFIA) for spectrophotometric determination of methamphetamine coupled with solvent extraction. Talanta. 2005 Dec 15;68(2):253-5. [DOI] [PMID]
9. He C, He Q, Deng C, Shi L, Fu Y, Cao H, et al. Determination of Methamphetamine Hydrochloride by highly fluorescent polyfluorene with NH2-terminated side chains. Synthetic Metals. 2011 Feb;161(3-4):293-7. [DOI]
10. Masteri-Farahani M, Mashhadi-Ramezani S, Mosleh N. Molecularly imprinted polymer containing fluorescent graphene quantum dots as a new fluorescent nanosensor for detection of methamphetamine. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 2020 Mar;229:118021. [DOI] [PMID]
11. Hassanzadeh J, Khataee A, Lotfi R. Sensitive fluorescence and chemiluminescence procedures for methamphetamine detection based on CdS quantum dots. Microchemical Journal. 2017 May;132:371-7. [DOI]
12. Takahashi F, Nitta S, Shimizu R, Shoji T, Tatsumi H, Jin J. Sensitive screening of methamphetamine stimulant using potential-modulated electrochemiluminescence. Analytica Chimica Acta. 2022 Jan;1191:339229. [DOI] [PMID]
13. Jiang L, Yang Y, Tu Y. A new strategy to develop the disposable label-free immunosensor with electrochemiluminescent probing. Journal of Electroanalytical Chemistry. 2015 Jun;747:136-42. [DOI]
14. McGeehan J, Dennany L. Electrochemiluminescent detection of methamphetamine and amphetamine. Forensic Science International. 2016 Jul;264:1-6. [DOI] [PMID]
15. Phonchai A, Janchawee B, Prutipanlai S, Thainchaiwattana S. Solid phase extraction for GC-FID determination of 3,4-methylenedioxymethamphetamine (MDMA), 3,4-methylenedioxyamphetamine (MDA) and methamphetamine (MA) in human urine. J Anal Chem. 2012 Feb 1;67(2):122-30. [DOI]
16. Rajabi M, Ghassab N, Hemmati M, Asghari A. Emulsification microextraction of amphetamine and methamphetamine in complex matrices using an up-to-date generation of eco-friendly and relatively hydrophobic deep eutectic solvent. Journal of Chromatography A. 2018 Nov;1576:1-9. [DOI] [PMID]
17. Kumazawa T, Hasegawa C, Lee XP, Hara K, Seno H, Suzuki O, et al. Simultaneous determination of methamphetamine and amphetamine in human urine using pipette tip solid-phase extraction and gas chromatography-mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis. 2007 Jun 28;44(2):602-7. [DOI] [PMID]
18. Lee S, Park Y, Yang W, Han E, Choe S, In S, et al. Development of a reference material using methamphetamine abusers' hair samples for the determination of methamphetamine and amphetamine in hair. Journal of Chromatography B. 2008 Apr 1;865(1-2):33-9. [DOI] [PMID]
19. Akhgari M, Bahmanabadi L, Sardari Iravani FS, Jokar F. Forensic laboratory validation of immunochromatography and gas chromatography/mass spectrometry methods for the detection of methamphetamine and amphetamine in postmortem urine specimens. Toxicologie Analytique et Clinique. 2021 Jun;33(2):109-15. [DOI]
20. Adcock JL, Barrow CJ, Barnett NW, Conlan XA, Hogan CF, Francis PS. Chemiluminescence and electrochemiluminescence detection of controlled drugs. Drug Testing and Analysis. 2011 Mar;3(3):145-60. [DOI] [PMID]
21. Takeuchi K, Ibusuki T. Determination of traces of hydrogensulfite by chemiluminescence with cerium(IV) sulfate as the reagent. Analytica Chimica Acta. 1985;174:359-63. [DOI]
22. Zhang S, Zhuang Y, Ju H. Flow‐Injection Chemiluminescence Determination of Papaverine Using Cerium(IV)‐Sulfite System. Analytical Letters. 2004;37(1):143-55. [DOI]
23. Adcock JL, Francis PS, Barnett NW. Chemiluminescence spectra for the oxidation of sulphite in the presence of fluorescent and non-fluorescent enhancers. Analytica Chimica Acta. 2009 Oct;652(1-2):303-7. [DOI] [PMID]
24. Xie Z, Ouyang X, Guo L, Lin X, Chen G, Xie Z, et al. Determination of carbofuran by flow‐injection with chemiluminescent detection, Determination of carbofuran by flow‐injection with chemiluminescent detection. Luminescence, Luminescence. 2005 May 1;20, 20(3, 3):226, 226-30, 230. [DOI] [PMID]
25. Zhang S, Wu Y, Li H. Flow injection chemiluminescence determination of N-tetrahydrobenzothiazolyl imines. The Analyst. 2000;125(4):753-7. [DOI]
26. Deming SN, Morgan SL. Teaching the fundamentals of experimental design. Analytica Chimica Acta. 1983;150:183-98. [DOI]
27. Huang Y, Zhang C, Zhang X, Zhang Z. Chemiluminescence of sulfite based on auto-oxidation sensitized by rhodamine 6G. Analytica Chimica Acta. 1999 May 26;391(1):95-100. [DOI]
28. Molins-Legua C, Campíns-Falcó P, Sevillano-Cabeza A. Automated pre-column derivatization of amines in biological samples with dansyl chloride and with or without post-column chemiluminescence formation by using TCPO-H2O2. Analyst. 1998 Dec;123(12):2871-6. [DOI] [PMID]
29. Hayakawa K, Imaizumi N, Ishikura H, Minogawa E, Takayama N, Kobayashi H, et al. Determination of methamphetamine, amphetamine and piperidine in human urine by high-performance liquid chromatography with chemiluminescence detection. Journal of Chromatography A. 1990 Aug 31;515:459-66. [DOI] [PMID]
30. Takayama N, Tanaka S, Hayakawa K. Determination of Stimulants in a Single Human Hair Sample by High-Performance Liquid Chromatographic Method with Chemiluminescence Detection. Biomedical Chromatography. 1997;11(1):25-8. https://doi.org/10.1002/(SICI)1099-0801(199701)11:1<25::AID-BMC615>3.0.CO;2-Y [DOI]
31. Sun J, Xu X, Wang C, You T. Analysis of amphetamines in urine with liquid-liquid extraction by capillary electrophoresis with simultaneous electrochemical and electrochemiluminescence detection. ELECTROPHORESIS. 2008;29(19):3999-4007. [DOI] [PMID]
32. Masteri-Farahani M, Mashhadi-Ramezani S, Mosleh N. Molecularly imprinted polymer containing fluorescent graphene quantum dots as a new fluorescent nanosensor for detection of methamphetamine. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 2020 Mar;229:118021. [DOI] [PMID]
33. Mandani S, Rezaei B, Ensafi AA. Sensitive imprinted optical sensor based on mesoporous structure and green nanoparticles for the detection of methamphetamine in plasma and urine. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 2020 Apr;231:118077. [DOI] [PMID]

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