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Health Science Monitor 2026, 5(1): 1-3 |
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Yazdan Nasab N, Hormati Oughoulbaig A H, Asadi A. Potential Role of Physical Activity in Hantavirus Prevention and Recovery. Health Science Monitor 2026; 5 (1) :1-3
URL: http://hsm.umsu.ac.ir/article-1-296-en.html
URL: http://hsm.umsu.ac.ir/article-1-296-en.html
Department of Sport Physiology, Faculty of Educational Sciences and Psychology, University of Mohaghegh Ardabili, Ardabil, Iran
Abstract: (26 Views)
Dear Editor,
Hantavirus infection remains a serious zoonotic illness that causes serious problems in the human heart, lungs, and kidneys. The virus is usually spread through the inhalation of aerosolized particles contaminated with rodent urine, saliva, or feces, and it has been identified as a public health threat in various countries across the world. Hantavirus infections have been reported across Asia, Europe, and the Americas, with thousands of cases of hemorrhagic fever with renal syndrome (HFRS) occurring annually worldwide. In the Americas, hantavirus cardiopulmonary syndrome (HCPS) remains a rare but highly fatal disease, with reported case-fatality rates often exceeding 30%. Despite extensive research on the epidemiology, transmission, and clinical manifestations of hantavirus infection, the potential role of physical activity in prevention and recovery remains underexplored.
Regular physical activity is widely recognized as an important modulator of immune function. Exercise at a moderate level has been demonstrated to promote immune cell circulation, strengthen immunological surveillance, and lessen persistent systemic inflammation. Previous studies suggest that physically active individuals may be less susceptible to infectious diseases and may experience improved outcomes following viral infections, according to earlier research. Additionally, exercise improves pulmonary and cardiovascular health, which may be especially important in cases of HCPS, where respiratory compromise is a significant clinical problem.
Hantavirus infection remains a serious zoonotic illness that causes serious problems in the human heart, lungs, and kidneys. The virus is usually spread through the inhalation of aerosolized particles contaminated with rodent urine, saliva, or feces, and it has been identified as a public health threat in various countries across the world. Hantavirus infections have been reported across Asia, Europe, and the Americas, with thousands of cases of hemorrhagic fever with renal syndrome (HFRS) occurring annually worldwide. In the Americas, hantavirus cardiopulmonary syndrome (HCPS) remains a rare but highly fatal disease, with reported case-fatality rates often exceeding 30%. Despite extensive research on the epidemiology, transmission, and clinical manifestations of hantavirus infection, the potential role of physical activity in prevention and recovery remains underexplored.
Regular physical activity is widely recognized as an important modulator of immune function. Exercise at a moderate level has been demonstrated to promote immune cell circulation, strengthen immunological surveillance, and lessen persistent systemic inflammation. Previous studies suggest that physically active individuals may be less susceptible to infectious diseases and may experience improved outcomes following viral infections, according to earlier research. Additionally, exercise improves pulmonary and cardiovascular health, which may be especially important in cases of HCPS, where respiratory compromise is a significant clinical problem.
Keywords: Immunomodulation, Physical activity, Prevention and control, Rehabilitation, Hantavirus infections
Type of Study: Letter to Editor |
Subject:
Health Promotion, Protection, and Disease Control
Received: 2025/12/17 | Accepted: 2026/01/7 | Published: 2026/02/11
Received: 2025/12/17 | Accepted: 2026/01/7 | Published: 2026/02/11
References
1. Hamid K, Sathyanarayanan SP, Naim T, Hamza M, Mahmood Baig MO, Sitta EA. Hantavirus Cardiopulmonary Syndrome and Diffuse Alveolar Hemorrhage in the Era of COVID-19. Case Rep Infect Dis. 2021; 8800500.doi: 10.1155/2021/8800500. [DOI] [PMID] [PMCID]
2. Wang J, Zhao W, Ding J, Li Y. The effect of physical activity on anti-infection immunity: a review. Health Inf Sci Syst, 2025;13(1): p. 45.doi: 10.1007/s13755-025-00360-8. [DOI] [PMID] [PMCID]
3. Abdoler, E.A. and P.N. Malani, What Is Hantavirus? Jama. 2025; 334(1): 98.doi: 10.1001/jama.2025.5014. [DOI] [PMID]
4. Prossegger J, Huber D, Grafetstätter C, Pichler C, Braunschmid H, Weisböck-Erdheim R, et al.Winter Exercise Reduces Allergic Airway Inflammation: A Randomized Controlled Study. Int J Environ Res Public Health. 2019; 16(11).doi: 10.3390/ijerph16112040. [DOI] [PMID] [PMCID]
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