Volume 4, Issue 4 (November 2025)                   Health Science Monitor 2025, 4(4): 304-309 | Back to browse issues page


XML Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Mehranfar S, Parvishi A, Heidari M, Ravanyar L. Investigating Factors Associated with Delays in Referral, Diagnosis, and Treatment of Patients with Cancer in Reference Oncology Hospitals in West Azerbaijan Province. Health Science Monitor 2025; 4 (4) :304-309
URL: http://hsm.umsu.ac.ir/article-1-254-en.html
Department of Immunology and Genetics, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran
Abstract:   (63 Views)
Background Cancer is a complex condition that requires a multidisciplinary approach to achieve timely diagnosis and treatment. Early initiation of treatment is essential for improving clinical outcomes. This study aimed to identify and analyze the factors associated with delays across the cancer care pathway in reference oncology hospitals in West Azerbaijan Province.
Methods This cross-sectional study included 74 parents of pediatric patients and 212 adult patients diagnosed with different types of cancer. Data were collected through structured questionnaires and in-person interviews after obtaining informed consent.
Results The main factors contributing to delays in initiating treatment were high treatment costs, poor perceived prognosis, fear of treatment, religious or superstitious beliefs, limited family support, preference for herbal or traditional remedies, and prolonged turnaround time for pathology reports.
Conclusion Improving public education regarding early cancer symptoms, strengthening communication and collaboration between healthcare providers and the health system, and ensuring patients receive adequate and comprehensible information may enhance timely care-seeking and support patients’ long-term adherence to treatment.
Full-Text [PDF 318 kb]   (30 Downloads)    
Type of Study: Research Article | Subject: Applied Biostatistics and Epidemiology
Received: 2025/07/13 | Accepted: 2025/10/17 | Published: 2025/11/19

References
1. Zhang X, Yang L, Liu S, Cao LL, Wang N, Li HC, et al. [Interpretation on the report of global cancer statistics 2022]. Zhonghua Zhong Liu Za Zhi. 2024;46(7):710-21. [Google Scholar]
2. Sheikh M, Shakeri R, Poustchi H, Pourshams A, Etemadi A, Islami F, et al. Opium use and subsequent incidence of cancer: results from the Golestan Cohort Study. Lancet Glob Health. 2020;8(5):e649-e60. doi: 10.1016/S2214-109X(20)30059-0 [DOI] [PMID]
3. Etemadi A, Abnet CC, Kamangar F, Islami F, Khademi H, Pourshams A, et al. Impact of body size and physical activity during adolescence and adult life on overall and cause-specific mortality in a large cohort study from Iran. Eur J Epidemiol. 2014;29:95-109. doi: 10.1007/s10654-014-9883-6 [DOI] [PMID] [PMCID]
4. Hadji M, Marzban M, Rashidian H, Naghibzadeh-Tahami A, Gholipour M, Mohebbi E, et al. Opium use and risk of colorectal cancer: a multi-center case-referent study in Iran. Acta Oncol. 2023;62(12):1661-8. doi: 10.1080/0284186X.2023.2276326 [DOI] [PMID]
5. Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209-49. doi: 10.3322/caac.21660 [DOI] [PMID]
6. Roshandel G, Ghanbari-Motlagh A, Partovipour E, Salavati F, Hasanpour-Heidari S, Mohammadi G, et al. Cancer incidence in Iran in 2014: results of the Iranian National Population-based Cancer Registry. Cancer Epidemiol. 2019;61:50-8. doi: 10.1016/j.canep.2019.05.009 [DOI] [PMID]
7. Asgarian F, Mirzaei M, Asgarian S, Jazayeri M. Epidemiology of breast cancer and the age distribution of patients over a period of ten years. 2016. [Google Scholar]
8. Amori N, Aghajani M, Asgarian F, Jazayeri M. Epidemiology and trend of common cancers in Iran (2004-2008). Eur J Cancer Care (Engl). 2017;26(5):e12449. doi: 10.1111/ecc.12449 [DOI] [PMID]
9. Chan CMH, Wan Ahmad WA, MD Yusof M, Ho GF, Krupat E. Effects of depression and anxiety on mortality in a mixed cancer group: a longitudinal approach using standardised diagnostic interviews. Psychooncology. 2015;24(6):718-25. doi: 10.1002/pon.3714 [DOI] [PMID]
10. Berry DA, Cronin KA, Plevritis SK, Fryback DG, Clarke L, Zelen M, et al. Effect of screening and adjuvant therapy on mortality from breast cancer. N Engl J Med. 2005;353(17):1784-92. doi: 10.1056/NEJMoa050518 [DOI] [PMID]
11. Walter F, Webster A, Scott S, Emery J. The Andersen Model of Total Patient Delay: a systematic review of its application in cancer diagnosis. J Health Serv Res Policy. 2012;17(2):110-8. doi: 10.1258/jhsrp.2011.010113 [DOI] [PMID] [PMCID]
12. Ermiah E, Abdalla F, Buhmeida A, Larbesh E, Pyrhönen S, Collan Y. Diagnosis delay in Libyan female breast cancer. BMC Res Notes. 2012;5:1-8. doi: 10.1186/1756-0500-5-452 [DOI] [PMID] [PMCID]
13. Dereje N, Addissie A, Worku A, Assefa M, Abraha A, Tigeneh W, et al. Extent and Predictors of Delays in Diagnosis of Cervical Cancer in Addis Ababa, Ethiopia: A Population-Based Prospective Study. JCO Glob Oncol. 2020(6):277-84. doi: 10.1200/JGO.19.00242 [DOI] [PMID] [PMCID]
14. Vivien YWC, Noor N. An Examination of Sociocultural Factors Influencing Lifestyles, Health and Health Seeking Behaviour: A Case Study of Malaysian Chinese Cancer Survivors: Kulliyyah of Islamic Revealed Knowledge & Human Sciences, International. 2012. [Google Scholar]
15. Agodirin OS, Aremu I, Rahman GA, Olatoke SA, Akande HJ, Oguntola AS, et al. Prevalence of Themes Linked to Delayed Presentation of Breast Cancer in Africa: A Meta-Analysis of Patient-Reported Studies. JCO Glob Oncol. 2020(6):731-42. doi: 10.1200/JGO.19.00402 [DOI] [PMID] [PMCID]
16. Neal R, Tharmanathan P, France B, Din N, Cotton S, Fallon-Ferguson J, et al. Is increased time to diagnosis and treatment in symptomatic cancer associated with poorer outcomes? Systematic review. Br J Cancer. 2015;112(1):S92-S107. doi: 10.1038/bjc.2015.48 [DOI] [PMID] [PMCID]
17. Hameed Khaliq I, Mahmood HZ, Sarfraz MD, Masood Gondal K, Zaman S. Pathways to care for patients in Pakistan experiencing signs or symptoms of breast cancer. Breast. 2019;46:40-7. doi: 10.1016/j.breast.2019.04.005 [DOI] [PMID]
18. Mohanti BK. Estimating the economic burden of cancer at a tertiary public hospital: a study at the all India Institute of Medical Sciences. 2011. [Google Scholar]
19. Ezeome ER, Anarado AN. Use of complementary and alternative medicine by cancer patients at the University of Nigeria Teaching Hospital, Enugu, Nigeria. BMC Complement Altern Med. 2007;7:1-8. doi: 10.1186/1472-6882-7-28 [DOI] [PMID] [PMCID]
20. Dang‐Tan T, Trottier H, Mery LS, Morrison HI, Barr RD, Greenberg ML, et al. Delays in diagnosis and treatment among children and adolescents with cancer in Canada. Pediatr Blood Cancer. 2008;51(4):468-74. doi: 10.1002/pbc.21600 [DOI] [PMID]
21. Shay V, Fattal-Valevski A, Beni-Adani L, Constantini S. Diagnostic delay of pediatric brain tumors in Israel: a retrospective risk factor analysis. Childs Nerv Syst. 2012;28(1):93-100. doi: 10.1007/s00381-011-1564-0 [DOI] [PMID]
22. Balmant NV, Silva NdP, Santos MdO, Reis RdS, Camargo Bd. Delays in the health care system for children, adolescents, and young adults with bone tumors in Brazil. J Pediatr (Rio J). 2019;95. doi: 10.1016/j.jped.2018.07.003 [DOI] [PMID]

Add your comments about this article : Your username or Email:
CAPTCHA

Send email to the article author


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2026 All Rights Reserved | Health Science Monitor

Designed & Developed by : Yektaweb