Volume 3, Issue 1 (January 2024)                   Health Science Monitor 2024, 3(1): 60-68 | Back to browse issues page


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Nikpo M, Houshmand H, Ghaemi M R, Rasouli J. Relationship between quality of life and disease severity of children with atopic dermatitis. Health Science Monitor 2024; 3 (1) :60-68
URL: http://hsm.umsu.ac.ir/article-1-116-en.html
Department of Allergy and Clinical Immunology, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran
Abstract:   (471 Views)
Background & Aims: Atopic dermatitis (AD) has a detrimental impact on the quality of life (QoL) for both patients and their families. Our investigation delved into the correlation between the severity of the disease and the QoL experienced by individuals with AD.
Materials & Methods: This cross-sectional descriptive-analytical study included AD children, between 0 to 16 years of age, along with their parents. The influence of childhood AD on parents' QoL was studied using several questionnaires, which measures four areas of physical health, mental health, social relations, and environmental health.
Results: Of 100 AD children, 52% were boys and 48% were girls with a mean age of 5.96 ± 4.72 years. Ninety percent of children had moderate AD. The mean score of QoL for children aged 5-16 years (CDQOL questionnaire) was 17.51, and for children aged 0-4 years (IDQOL questionnaire) was 15.80. The mean score of parents' QoL, according to the FDLQI questionnaire, was 13.90, and according to the DFI questionnaire, it was 6.39. The mean scores of health and QoL in four areas of physical health, mental health, social relations, and environmental health were 20.79, 17.75, 9.72, and 25.9, respectively. There was a significant correlation between disease severity and scores obtained from CDQOL and IDQOL questionnaires (p < 0.001).  
Conclusion: Childhood AD had a greater impact on QoL of parents in the areas of social relationships and psychological well-being. The influence of AD on the QoL of family members is significant, and this should be taken into account in the therapeutic process.
Full-Text [PDF 272 kb]   (134 Downloads)    
Type of Study: Research | Subject: General
Received: 2023/04/22 | Accepted: 2023/11/18 | Published: 2024/01/6

References
1. Von Kobyletzki LB, Janson S, Hasselgren M, Bornehag C-G, Svensson Å. Evaluation of a parental questionnaire to identify atopic dermatitis in infants and preschool children. Journal of allergy. 2012;2(3):5-12. [DOI] [PMID] [PMCID]
2. Lifschitz C. The impact of atopic dermatitis on quality of life. Ann Nutr Metab. 2015;66 Suppl 1:34-40. doi: 10.1159/000370226 [DOI] [PMID]
3. Kapur S, Watson W, Carr S. Atopic dermatitis. Allergy Asthma Clin Immunol. 2018 Sep 12;14(Suppl 2):52. doi: 10.1186/s13223-018-0281-6 [DOI] [PMID] [PMCID]
4. Bantz SK, Zhu Z, Zheng T. The Atopic March: Progression from Atopic Dermatitis to Allergic Rhinitis and Asthma. J Clin Cell Immunol. 2014 Apr;5(2):202. doi: 10.4172/2155-9899.1000202 [DOI] [PMID] [PMCID]
5. Van Valburg RW, Willemsen MG, Dirven-Meijer PC, Oranje AP, Van Der Wouden JC, Moed H. Quality of life measurement and its relationship to disease severity in children with atopic dermatitis in general practice. Acta dermato-venereologica. 2011;91(2):147-51. [DOI] [PMID]
6. Kalmarzi RN, Khazaei Z, Shahsavar J, Gharibi F, Tavakol M, Khazaei S, et al. The impact of allergic rhinitis on quality of life: a study in western Iran. Biomedical Research and Therapy. 2017;4(9):1629-37. [DOI]
7. Miller GE, Chen E, Parker KJ. Psychological stress in childhood and susceptibility to the chronic diseases of aging: moving toward a model of behavioral and biological mechanisms. Psychol Bull. 2011 Nov;137(6):959-97. doi: 10.1037/a0024768 [DOI] [PMID] [PMCID]
8. Rambod M, Sharif F, Molazem Z, Khair K, von Mackensen S. Health-Related Quality of Life and Psychological Aspects of Adults With Hemophilia in Iran. Clin Appl Thromb Hemost. 2018 Oct;24(7):1073-1081. doi: 10.1177/1076029618758954 [DOI] [PMID] [PMCID]
9. Lee DG, Gui XY, Mukovozov I, Fleming P, Lynde C. Sleep Disturbances in Children With Atopic Dermatitis: A Scoping Review. J Cutan Med Surg. 2023 Mar-Apr;27(2):157-164. doi: 10.1177/12034754231159337 [DOI] [PMID] [PMCID]
10. Dwiyana RF, Nuraeni L, Diana IA, Effendi RMRA, Gondokaryono SP, Ruchiatan K, Hindritiani R, Gunawan H. Melatonin and Sleep Disturbances in Children With Atopic Dermatitis. Clin Cosmet Investig Dermatol. 2022 Jun 27;15:1175-1182. doi: 10.2147/CCID.S366854 [DOI] [PMID] [PMCID]
11. Xu YC, Wang JP, Zhu WJ, Li P. Childhood atopic dermatitis as a precursor for developing attention deficit/hyperactivity disorder. Int J Immunopathol Pharmacol. 2020 Jan-Dec;34:2058738420962902. doi: 10.1177/2058738420962902 [DOI] [PMID] [PMCID]
12. Sur M, Boca AN, Ilies RF, Floca E, Tataru A, Sur L. Correlation between quality of life and disease severity of pediatric patients with atopic dermatitis. Exp Ther Med. 2020 Dec;20(6):189. doi: 10.3892/etm.2020.9319 [DOI] [PMID] [PMCID]
13. Pusti_sek N, Vurnek _Zivkovi_c M, _Situm M. Quality of life in families with children with atopic dermatitis. Pediatr Dermatol 2016; 33: 28-32. [DOI] [PMID]
14. Ra_znatovi_c Djurovi_c M, Jankovi_c J, Tomi_c Spiri_c V, Jankovi_c S. Healthrelated quality of life in children with moderate to severe atopic dermatitis. Acta Dermatovenerol Croat 2015; 23: 178-184. [Google Scholar]
15. Kalmarzi RN, Zamani A, Fathallahpour A, Ghaderi E, Rahehagh R, Kooti W. The relationship between serum levels of vitamin D with asthma and its symptom severity: A case-control study. Allergologia et immunopathologia. 2016. [Google Scholar]
16. Singh B, Thandar Y, Balakrishna Y, Mosam A. The quality of life of caregivers of children with atopic dermatitis in a South African setting. J Child Health. 2019;13(2):63-8. [Google Scholar]
17. Shariati M, Nasiri Kalmarzi R, Abaei Hasani S, Goodarzi E, Hasanzadeh J, Ataee P, et al. The impact Atopic dermatitis on the life quality of childrens 1-6 year. Int J Pediatr. 2018;6(1):7003-11. [Google Scholar]
18. Hadi HA, Tarmizi AI, Khalid KA, Gajdács M, Aslam A, Jamshed S. The Epidemiology and Global Burden of Atopic Dermatitis: A Narrative Review. Life (Basel). 2021 Sep 9;11(9):936. doi: 10.3390/life11090936 [DOI] [PMID] [PMCID]
19. Soares GB, Orfali RL, Averbach BL, Yosipovitch G, Aoki V. Atopic Dermatitis in Latin America: Considerations on Epidemiology, Clinical and Laboratory Features, Ethnic/Racial Variations, and Therapeutic Management. Journal of Clinical Medicine. 2023 May 11;12(10):3419. [DOI] [PMID] [PMCID]
20. Sur M, Boca AN, Ilies RF, Floca E, Tataru A, Sur L. Correlation between quality of life and disease severity of pediatric patients with atopic dermatitis. Experimental and Therapeutic Medicine. 2020 Dec 1;20(6):1-12. [DOI] [PMID] [PMCID]
21. Xu X, van Galen LS, Koh MJ, Bajpai R, Thng S, Yew YW, et al. Factors influencing quality of life in children with atopic dermatitis and their caregivers: a cross-sectional study. Scientific reports. 2019 Nov 5;9(1):15990. [DOI] [PMID] [PMCID]
22. Gabes M, Chamlin SL, Lai JS, Cella D, Mancini AJ, Apfelbacher CJ. Development of a validated short‐form of the Childhood Atopic Dermatitis Impact Scale, the CADIS‐SF15. Journal of the European Academy of Dermatology and Venereology. 2020 Aug;34(8):1773-8. [DOI] [PMID]
23. Ben‐Gashir MA, Seed PT, Hay RJ. Quality of life and disease severity are correlated in children with atopic dermatitis. British Journal of Dermatology. 2004 Feb 1;150(2):284-90 [DOI] [PMID]
24. Holm J, Agner T, Clausen ML, Thomsen S. Quality of life and disease severity in patients with atopic dermatitis. J Eur Dermatol Venereol. 2016;30(10):1760-7. [DOI] [PMID]
25. Marciniak J, Reich A, Szepietowski JC. Quality of life of parents of children with atopic dermatitis. Acta Derm Venereol. 2017;97(6-7):711-4. [DOI] [PMID]
26. Tadros A, Vergou T, Stratigos AJ, Tzavara C, Hletsos M, Katsambas A, et al. Psoriasis: is it the tip of the iceberg for quality of life of patients and their families? J Eur Acad Dermatol Venereol 2011; 25: 1282-1287. [DOI] [PMID]
27. Monti F, Agostini F, Gobbi F, Neri E, Schianchi S, Arcangeli F. Quality of life measures in Italian children with atopic dermatitis and their families. Ital J Pediatr 2011; 22: 37-59. [DOI] [PMID] [PMCID]
28. Al Robaee AA, Shahzad M. Impairment quality of life in families of children with atopic dermatitis. Acta Dermatovenerol Croat 2010; 18: 243-247. [Google Scholar]
29. Aziah M, Rosnah T, Mardziah A, Norzila M. Childhood atopic dermatitis: a measurement of quality of life and family impact. Med J Malaysia. 2002;57(3):329-39. [Google Scholar]
30. A Al Robaee A, Shahzad M. Impairment quality of life in families of children with atopic dermatitis. Acta Derm Venerol Croatica. 2010;18(4):20-25. [Google Scholar]
31. Chernyshov PV, Jirakova A, Ho R, Moed H, Caldeira AP, Alvarenga TM, et al. An international multicenter study on quality of life and family quality of life in children with atopic dermatitis. Indian J Dermatol Venereol Leprol. 2013;79(1);15-20. [DOI] [PMID]
32. Kim DH, Li K, Seo SJ, et al. Quality of life and disease severity are correlated in patients with atopic dermatitis. J Korean Med Sci. 2012;27:1327-32. [DOI] [PMID] []
33. Alzolibani AA. Impact of atopic dermatitis on the quality of life of Saudi children. Saudi Med J. 2014;35:391-6. [Google Scholar]
34. Chernyshov PV. Gender differences in health-related and family quality of life in young children with atopic dermatitis. Int J Dermatol. 2012;51:290-4. [DOI] [PMID]
35. Balci D, Sangün Ö, Inandi T. Cross validation of the Turkish version of Children's Dermatology Life Quality Index. J Turk Acad Dermatol. 2007;1:71402a. [Google Scholar]

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