Health Science Monitor

en Study and prediction of the case-fatality rate (CRF) of COVID-19 based on patient’s medical information referred to Dr. Masih Daneshvari Hospital in Tehran عمومى General پژوهشي Research Article Background & Aims:  Coronavirus disease 2019 (COVID-19) is an acute respiratory syndrome that despite global health efforts to prevent its spread, it still has high fatality rates in many countries. Materials & Methods: Based on the medical information of 4,372 COVID-19 patients referring to Dr. Masih Daneshvari Hospital in Tehran, Iran, the case-fatality rate (CFR) for COVID-19 was calculated, and the trend of this index was assessed using the artificial neural network (ANN) model. Results: In this study, the CFR for COVID-19 reduced by an average of 0.4% per day and reached 4.43% during 50 days of the epidemic onset. Predicting the daily trend of this index using ANN model also showed a very gentle downward trend. According to the prediction of this model, during the first 100 days and also the second 100 days from the COVID-19 epidemic onset, the CFR for this disease decreased by an average of 0.03% and 0.01% per day, and reached 3.87% and 3.05%, respectively, Conclusion: The use of CFR for COVID-19 and prediction of the trend of this index for the future can provide valuable information on the diagnosis of the disease severity and evaluation of the effectiveness of control and treatment strategies, as well as assessment of the health care. Coronavirus, Covide-19, Case-fatality rate (CFR), Artificial neural networks (ANNs), Prediction 131 137 http://hsm.umsu.ac.ir/browse.php?a_code=A-10-76-4&slc_lang=en&sid=1 Mehdi Kazempour Dizaji mkazempour@sbmu.ac.ir 10031947532846001540 10031947532846001540 Yes Mycobacteriology Research Center (MRC),National Research Institute of Tuberculosis and Lung Disease (NRITLD) , Shahid Beheshti University of Medical Sciences, Tehran, Iran Ali Zare mkazempour@sbmu.ac.ir 10031947532846001541 10031947532846001541 No Mycobacteriology Research Center (MRC),National Research Institute of Tuberculosis and Lung Disease (NRITLD) , Shahid Beheshti University of Medical Sciences, Tehran, Iran Payam Tabarsi mkazempour@sbmu.ac.ir 10031947532846001542 10031947532846001542 No Clinical Tuberculosis and Epidemiology, research center, National Research Institute of Tuberculosis and Lung Disease (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.