Health Science Monitor

en Modeling the survival of patients with tuberculosis based on the model of artificial neural networks عمومى General پژوهشي Research Article Background & Aims:  The development of treatment methods and increasing the survival of patients with tuberculosis (TB) has led to the complication of relationships between independent and dependent variables associated with this disease. Therefore, it is important to use new methods to model the TB process that can accurately estimate the current situation. This study aimed to model the survival of patients with tuberculosis based on the model of perceptron artificial multilayer neural network (MLP-ANN). Materials and Methods: In this retrospective cohort study, the data was collected from 2366 TB patients who were treated in Dr. Masih Daneshvari Hospital in Tehran from 2005 to 2015. To model the predictive power of survival in TB patients, an MLP-ANN model consisting of three layers was applied. Results: The results of this study showed that based on the MLP-ANN model, the correct predictive power of survival in TB patients is 88.4%. In this study, the variables of patients' age and family size as very effective variables also variables of patients’ gender, marital status, education, adverse drug effects, exposure to cigarette smoke, imprisonment, pulmonary tuberculosis, and AIDS as effective variables in predicting the survival of patients were diagnosed. Conclusion: In the model of artificial neural networks, no restrictions are considered for the data structure and the type of relationship between variables. Therefore, these models with their flexibility and high accuracy can be one of the best methods for modeling health data. Perceptron artificial neural network, Survival, Tuberculosis, Modeling 64 73 http://hsm.umsu.ac.ir/browse.php?a_code=A-10-76-1&slc_lang=en&sid=1 Mehdi Kazempour Dizaji mkazempour@sbmu.ac.ir 10031947532846001493 10031947532846001493 Yes Mycobacteriology Research Center (MRC), National Research Institute of Tuberculosis and Lung Disease (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran Majid Marjani mkazempour@sbmu.ac.ir 10031947532846001494 10031947532846001494 No Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis and Lung Disease (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran. Payam Tabarsi mkazempour@sbmu.ac.ir 10031947532846001495 10031947532846001495 No Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis and Lung Disease (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran. Mohammad Varahram mkazempour@sbmu.ac.ir 10031947532846001496 10031947532846001496 No Mycobacteriology Research Center (MRC), National Research Institute of Tuberculosis and Lung Disease (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran Ali Zare mkazempour@sbmu.ac.ir 10031947532846001497 10031947532846001497 No Department of Biostatistics, National Research Institute of Tuberculosis and Lung Disease (NRITLD) , Shahid Beheshti University of Medical Sciences, Tehran, Iran Mohammad Ali Emamhadi mkazempour@sbmu.ac.ir 10031947532846001498 10031947532846001498 No Department Forensic Medicine, School of Medicine Shahid Beheshti University of Medical Sciences, Tehran, Iran. Rahim Roozbahani mkazempour@sbmu.ac.ir 10031947532846001499 10031947532846001499 No Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis and Lung Disease (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran. Atefe Abedini mkazempour@sbmu.ac.ir 10031947532846001500 10031947532846001500 No Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Disease (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran. Parvane h Baghaei Shiva mkazempour@sbmu.ac.ir 10031947532846001501 10031947532846001501 No Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis and Lung Disease (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran. Afshin Moniri mkazempour@sbmu.ac.ir 10031947532846001502 10031947532846001502 No Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis and Lung Disease (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran. Mohammadreza Madani mkazempour@sbmu.ac.ir 10031947532846001503 10031947532846001503 No Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Disease (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.