en نظام‌های سلامت عمومی، سیاست‌گذاری و اقتصاد سلامت Health Policy, Management, and Economics پژوهشي Research Article <span style="font-size:12pt"><span style="line-height:16.0pt"><span new="" roman="" style="font-family:" times=""><b><i><span style="font-size:9.0pt">Background & Aims</span></i></b><b><span style="font-size:9.0pt">: </span></b><span style="font-size:9.0pt">Esophageal cancer is a research priority due to its invasive nature and poor prognosis. It ranks sixth in mortality among all forms of cancer and</span><span lang="EN-GB" style="font-size:9.0pt"> esophagectomy</span><span style="font-size:9.0pt"> is the most conventional treatment. Jejunostomy tube feeding can reduce complications in patients and hospital costs. This study aimed to evaluate the cost-effectiveness of jejunostomy tube feeding, as opposed to the common nutritional method. </span></span></span></span><br> <span style="font-size:12pt"><span style="line-height:16.0pt"><span new="" roman="" style="font-family:" times=""><b><i><span style="font-size:9.0pt">Materials & Methods</span></i></b><b><span style="font-size:9.0pt">:</span></b><span style="font-size:9.0pt"> A retrospective case-control study was conducted at a teaching hospital in Iran in 2015. The sample of the study included 100 candidates for esophagectomy. In the case group (enteral), a Jejunostomy tube was inserted for 50 patients undergoing esophagectomy. The control group (parenteral) consisted of 50 patients undergoing esophagectomy without jejunostomy tube. &nbsp;</span></span></span></span><br> <span style="font-size:12pt"><span style="line-height:16.0pt"><span new="" roman="" style="font-family:" times=""><b><i><span style="font-size:9.0pt">Results</span></i></b><b><span style="font-size:9.0pt">:</span></b><span style="font-size:9.0pt"> The median oral intake was on the third day in the case group, with a shorter hospital stay (P=0.02) compared to the control group. The mean total costs of hospitalization per patient </span><span lang="EN-GB" style="font-size:9.0pt">in the case group and in the control group were 2228 and 3666 US dollars, respectively. The cost-</span><span style="font-size:9.0pt">effectiveness ratio of the jejunostomy tube against the common nutritional method was about 40 US dollars per day of the median decrease in oral intake. &nbsp;</span></span></span></span><br> <b><i><span style="font-size:9.0pt"><span style="line-height:200%"><span new="" roman="" style="font-family:" times="">Conclusion</span></span></span></i><span style="font-size:9.0pt"><span style="line-height:200%"><span new="" roman="" style="font-family:" times="">: </span></span></span></b><span style="font-size:9.0pt"><span style="line-height:200%"><span new="" roman="" style="font-family:" times="">According to our findings, jejunostomy tube is cost-effective and preferable to the common nutritional method with a decreased median of oral intake start day, a decreased span of hospitalization, fewer complications in the nutritional support of the patients undergoing esophagectomy, and finally, more comfort for patients. The decrease in the average length of stay in hospitals is also important from the point of view of policymaking. So, this method can be a cost-effective alternative to the common nutritional method.</span></span></span> Cost- effectiveness, Esophageal cancer, Esophagectomy, Jejunostomy, Nutrition 210 216 http://hsm.umsu.ac.ir/browse.php?a_code=A-10-163-1&slc_lang=en&sid=1 Rahim Mahmodlou mahmodlou@umsu.ac.ir 10031947532846001651 10031947532846001651 No Professor. Department of general surgery, School of medicine, Urmia University of Medical Sciences, Urmia, West Azerbaijan, Iran Hasan Yusefzadeh yusefzadeh.h@umsu.ac.ir 10031947532846001652 10031947532846001652 No Associate Professor. Department of Health Economics and Management, School of Public Health, Urmia University of Medical Sciences, Urmia, West Azerbaijan, Iran Amin Farjami farjami.a@umsu.ac.ir 10031947532846001653 10031947532846001653 No Department of Surgery, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran Bahram Nabilou bnabil@umsu.ac.ir 10031947532846001654 10031947532846001654 Yes Associate Professor. Department of Health Economics and Management, School of Public Health, Social Determinants of Health Research Center, Urmia University of Medical Sciences, Urmia, Iran.